In 2023, the  United States Secretary of State, Antony Blinken  launched the Global Coalition to Address Synthetic Drug Threats.  The Coalition is designed to bring together a geographically, economically, and politically diverse group of stakeholders to produce action and results in response to the rise in synthetic drug threats. With over 140 countries and international organizations participating, the resolve of our global community in combatting the urgent challenges posed by synthetic drugs is clear.  The Coalition convenes through Working Group and Sub-Working Group meetings to identify and advance concrete actions and outcomes.

The coalition is guided by the Ministerial Declaration on Accelerating and Strengthening the Global Response to Synthetic Drugs, participating governments expressed their commitment to “taking into account input from civil society in Coalition objectives.”  As part of the efforts to solicit meaningful civil society input, the U.S. Department of State Bureau of International Narcotics and Law Enforcement and the Vienna and New York NGO Committees on Drugs (VNGOC & NYNGOC) are inviting civil society organizations to share written inputs, including recommendations, planned initiatives and good practice examples. 

You can find all inputs collected in the below table and selected inputs will also be featured on the Coalition website ( They will serve as a reference for governments to individually consider engagements opportunities and make commitments on specific initiatives. 

Civil society organizations working on synthetic drug related issues are invited to share their inputs through this online form:

We also encourage you to post your inputs on the NGO Marketplace:

OrganizationCountryInput to the work of the Global CoalitionWebsiteContact personContact email
A HAND TO HUMANITY ASSOCIATIONCameroonProtecting the Future: Promoting a Drug-Free School Environment in Africa and the World

Distinguished delegates
Esteemed colleagues
Ladies and gentlemen
It is with profound honour and a deep sense of responsibility that I stand before you today, representing A Hand to Humanity Association, to address the critical issue of synthetic drug threats and their devastating impact on our youth, both in Africa and around the world.
The rise of these deceptive substances, casts a dark shadow over our future, threatening the health and well-being of countless young people. It is imperative that we, as a global community, unite in our determination to combat this menace and protect the future of our children.
Our Recommendations:
Strengthening International Cooperation:
• Establish a global task force dedicated to combating synthetic drug trafficking and sharing intelligence among nations.
• Foster collaboration between law enforcement agencies, border control authorities, and intelligence services to dismantle criminal networks and disrupt supply chains.
• Promote international cooperation in research and development to enhance detection methods and develop effective treatment strategies.
Promoting Comprehensive Drug Education:
• Implement age-appropriate drug education programs in schools worldwide, starting from the primary level.
• Equip teachers with the knowledge and skills to deliver effective drug education lessons, utilizing innovative and engaging teaching methods.
• Develop culturally sensitive educational materials that resonate with students from diverse backgrounds.
• Foster open communication between students and teachers, creating a safe space for them to discuss drug-related issues without fear of judgment.
Empowering Parents and Communities:
• Organize workshops and awareness campaigns for parents and community members to educate them about the dangers of synthetic drugs and equip them with the tools to support their children.
• Establish strong partnerships between schools, families, and community organizations to create a unified front against drug abuse.
• Promote open communication and collaboration between parents and teachers to monitor students' behaviour and address potential issues early on.
Investing in Prevention and Treatment Programs:
• Allocate sufficient resources to develop and implement evidence-based prevention and treatment programs for individuals struggling with synthetic drug addiction.
• Ensure access to affordable and quality treatment services, including detoxification, rehabilitation, and ongoing support.
• Promote research into the long-term effects of synthetic drugs and develop effective strategies for prevention.
More information:
ACEIDCosta RicaThere is a need to reduce and/or eliminate criminalization, stigma and discrimination towards people who use drugs. This punitive and negative social or political context is considered a stuctural barrier to access to health and social services to prevent or treat drug use.

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Dalgarno InstituteAustraliaTaking the NOVEL out of NPS – Health Harms & Reducing Demand
Introduction only
‘Learning is education that transforms.’ Dalgarno Institute
Education changes behaviour, but what ‘kind’ of education does this and to what end?
Whilst we will examine key aspects of Harms done by New/Novel Psychoactive Substances, what we don’t’ want to do is waste your time simply inventorying descriptive data that may or may not give you some facts about this subject matter that you don’t already know.
We will attempt in this presentation to open up more proactive focus on the reducing of demand and diverting from NPS use.
One key framework for a behaviour transitioning educative process.
+ Aware – Information (Whilst a starting point of contemplation, giving ‘facts’ in a vacuum has little traction in behaviour change)
+ Move – Education (This is where knowledge is added giving facts some context for application and a potential direction)
+ Change – Learning (This is where knowledge is applied in a sustained direction with purpose, under tutelage for a specific outcome – This helps create new behaviours)
It is important to understand that teaching and learning mechanisms and modes have many elements and both the cognitive, (but more specifically) the affective domain education pedagogies are enhanced by both evidence-based practice, as well as, by practice based evidence.
This is no more evident than in indigenous cultural settings, and of growing importance in sub-cultural ‘tribal’ settings too.
Evidence-based Practice & Practice-based Evidence?
Efficacious pedagogies in the Affective Domain education arena include imperatives such as the contextualised sharing of relevant earned resiliency and lived experience with the learning audience. This is one of a few vital components of an education strategy, that seeks to develop proactive and protective behaviours in the child and emerging adult. Lived experience alone (i.e. substance user) is only valuable in a protective context when it is paired with the earned resiliency that empowered them to exit and stand from substance use and its harms, that proves valuable in the behaviour change education process.
“One with lived experience is seen by the client/student as an authentic knowledge holder.” Gemma Khodr – Indigenous Health & Alcohol CRE Forum September 2020

Dalgarno Institute – Research Team

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Drug Awareness FoundationUnited StatesAll hospitals should be adding fentanyl testing to their federal five tox screens.

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Drug Free AustraliaAustraliaPlease take the time to review to review The important Fourth Wave Report and comments by Scott Walton Chief Executive Officer, Millennium Health.
Most People who Used Fentanyl with the Other Primary Drivers of Overdose Death Used Fentanyl and Methamphetamine Only, Followed by Fentanyl and Cocaine Only or All Three Combined

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Fédération AddictionFranceThe Fédération Addiction is France's leading network of addictology structures and professionals. In particular, we run the "Analyse ton prod'" network, which brings together facilities offering drug analysis for harm reduction purposes: we defend free, anonymous access to drug analysis as an essential tool in any harm reduction policy.
For people who want to use drugs, drug analysis enables them to be better informed, to make informed choices and to implement individual and collective strategies to reduce the risks associated with the use of psychoactive products.
The "Analyse ton prod'" network is also a partner in the SINTES system run by the French Observatory of Drugs and Addictive Tendencies (OFDT), playing an active role in health monitoring and observing trends in product mix and the arrival of new substances.
In France, synthetic drugs, and in particular synthetic cathinones, are used in the context of chemsex: together with AIDES, the Fédération Addiction is leading the ARPA-Chemsex project, designed to model support and care for chemsex users by combining the skills of specialized addictology structures and LGBTI community health services, taking into account the specificities of the MSM public and the stigmatization issues associated with sexuality.

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Former Acting Board Chair of Law Enforcement Against Prohibition (LEAP); no current affiliation.United StatesThe “Undifference” Between Fentanyl and Heroin
American Addiction Centers explain some of the differences between two popularly used opioids in an article entitled, “Fentanyl vs. Heroin: An Opioid Comparison.”
Overdose fatalities involving heroin or fentanyl are rising. The Centers for Disease Control and Prevention (CDC) reports that close to 30,000 Americans died from an opioid overdose in 2014. Overdose deaths from synthetic opioids like fentanyl nearly doubled from 2013 to 2014, and heroin overdose fatalities quadrupled from 2002 to 2013, the CDC publishes. Yet public attitudes and political realities continue to resist harm-reduction remedies such as safe-injection sites, drug treatment centers, pharmaceutical-based addiction treatment, drug maintenance programs for persons addicted to drugs, widespread naloxone availability, clean needle distribution, drug-dealer licensing, and government inspection and regulation of legalized illicit drug products. Commenting on this sad reality regarding safe-injection sites, Illinois state Rep. LaShawn K. Ford commented on the political reality, noting that support for safe injection sites is “bad politics.”226 Reflecting that same popular sentiment, and not in my backyard sentiment (NIMBY), the Haymarket Center recently filed a civil rights lawsuit in federal court regarding a village’s denial of zoning relief to permit the conversion of a Holiday Inn into a disparately needed 240-bed, drug treatment facility in Itasca, Illinois, following two years of pleading, petitioning and thirty-five public hearings.227 Treatment centers, safe injection sites and legalized and labeled drugs could change the course of the deadly fentanyl overdose phenomenon, but lifesaving, healthy drug policy is counterintuitive and frightening to the current, vocal “silent majority.”

803 new synthetic drug concoctions were invented,160 deaths directly associated with drug use were up 6o%,161 less than 1% of the half of drug-trafficking revenues funneled into money laundering was seized (the whole of those revenues estimated to be $426-652 USD Billion),162 and illicit demand for ecstasy, cannabis and opioids was up by 33%, 17% and 16%, respectively.163 The 2009 Declaration and Plan continued to march society down the wrong, well-worn road — the 1961 Single Convention International Highway.” The Silver Bullet excerpts, Trinity Christian College, Gierach PowerPoint presentation, 30-minute Chicago cable-TV interview with Dan Bigg, E.
GEMPITA (Red Ribbon Independent Movement)IndonesiaMake policies that apply to all countries by looking at the facts that occur in problematic countriesInstagram : @yayasangempitaSamuel
Institute for Narcotics Studies and Analysis (INSA)IndiaWhat is concerning is the proclivity of synthetic drug use and its growing popularity amongst the users. Particularly in India, huge seizures of methamphetamine have raised alarms about its burgeoning use. The evolving landscape of processing, manufacturing and use with new actors and players have made it imperative to view the problem of tackling drug use with a new pair of lens.
New and potent drugs continue to make its way into the market from the laboratories and will continue to do so. India has a growing pharmaceutical, textile and chemical industry and does it is so much easier to procure precursor chemicals with lenient controls. This is certainly a catalyst and incentive for Mexican and African drug cartels to spread its tentacles to India, partnering with some pharmaceutical companies and Individuals and shift its processing and manufacturing operations to India.
Lets take the case of cocaine in India. In a report published in 2004, cocaine was not a commonly used illicit drug. Just about 0.01 % of the population used cocaine. By 2006, India emerged as a big cocaine market. By 2015, Mumbai was claimed to be the 'cocaine capital' of India followed by Delhi. This interestingly coincided with a global uptick in cocaine cultivation, manufacturing and trafficking followed by use. The extent of seizures went up from 8.667 kgs in 2021-22 to 310.21 kgs in 2022-23- up by a staggering 3479%. The retail price of cocaine went up from INR 4000 -5000 per gram in 2006 to INR 15.000 -20,000 per gram in 2023.
The resilience of the cocaine markets is surprising. New methods of 'cocaine camouflaging' as Black Cocaine, Liquid Cocaine and Cream Cocaine lends credence to the the existence of illicit laboratories in India which has the technology to extract cocaine from the above modes once successfully smuggled.
Coming back to India's tryst with precursor chemicals, ethyl acetate, one of the precursor chemicals for manufacturing the use of cocaine, is freely available in India. The market for ethyl acetate which was US$645.44 million in 2021 is expected to skyrocket to US$1200.88 million by 2029.
Indian consumer market for cocaine is growing and there are clear indications that India's role in the international cocaine trade is changing, with increase in use and seizures presenting a grim reality of the harms perpetrated by synthetic drug use. Kawal deep
Instituto RIAMexicoThe international drug control treaties, specifically the 1961 Single Convention on Drugs (SCD) does provide a pathway to legal markets, provided it is for medical or scientific purposes. A country could choose to undertake the cultivation of opium poppy production, duly notifying the International Narcotics Control Board (INCB) and establishing a government agency to oversee all aspects of the production chain, including the exportation to countries with an interest in providing a harm-reducing alternative to the illegal injection drugs market. Although we advocate for the full, legal regulation of all drugs for adult use, a poppy cultivation pilot project to export opium products could occur more quickly within a medicinal, therapeutic or research framework.

Numerous countries have implemented medical heroin programs (including Switzerland, Germany, and the UK), However, this policy proposal would also integrate a diversity of products and economic opportunities for communities that cultivate, rather than a pharmaceutical model that usually maintains such benefits within a singular company.

If Mexico were to opt for regulating opium for medicinal use, the country would send a notification to the INCB, identifying the area and geographical location of cultivation and the approximate quantity of opium that will be produced. A government agency would need to oversee all aspects, including determining licensed cultivators and administering the harvesting of the production. This agency could also integrate social equity mechanisms to ensure participation of communities most impacted by prohibition. The agency would have exclusive rights to import, export, and wholesale as well as maintain stocks and licenses held by manufacturers of opium alkaloids and medicinal opium, as defined in the 1961 SCD.

The Mexican government could be responsible for quality testing, analysis, and exportation; this legal framework would then permit other countries to purchase poppy tea, opium gum and other opium-based products (including heroin) from the country, as a life-saving harm reduction complement. An import and export authorization or certificate would need to be issued by the appropriate and relevant authorities in both the import and export countries.

Allowing for the legal production of poppy and opium gum would mean cultivating communities could legally protect their right to work, and all its encompassing benefits. A pilot project for the legal regulation of opium gum that envisions a social justice approach would include bring in vulnerable groups, especially youth and women, as well as repairing the harms of prohibition through licensing exclusivity. Providing a legal framework to work safely and with dignity would allow these families to access other basic services, such as education and healthcare, as well as reduce displacement and conflict caused by the militarised response to the prohibition of this industry.

The safe supply of opium gum and manually extracted heroin could improve harm reduction and treatment options worldwide, while providing economic opportunities for communities that cultivate poppy. People who use drugs, particularly those that inject drugs, can and must be provided with a broad range of products, including opium that can be smoked or eaten. Once people have a spectrum of options, they might choose to reduce injecting and, in that way, reduce undesired health consequences such as abscesses, overdoses or disease transmission. Offering a wider range of products, including poppy tea and opium gum, as well as heroin, would better meet the needs and rights of people who use drugs.

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International Helping for the YoungChadTo fight against synthetic drugs, civil society must have capacity building how to fight against synthetic drugs, to have a solution for generations Abdelkerim
International Movement for Advancement of Education Culture Social & Economic Development (IMAECSED)IndiaDrug abuse has a direct impact on major social and economic aspect of the nation. In the present growing trend of globalization and resilient digital economy there is no part of any country or region the world which is free from drug abuse. The connotation of drug is a phenomenon which is primarily used for medical or prescribed drug but due to its vast global supply chain and increasing productivity, pushing upwards its demand, as a result drug users are not within the parameter of prescribed or legal drug it is take turn mostly on synthetic or illegal drug.

Illicitly-manufactured synthetic drugs such as fentanyl, Tramadol, methamphetamine, captagon, MDMA, and ketamine threaten the health, security and well being of people around the world. Synthetic Drug Threats cut across both public health and criminal justice; within a country no single agency can provide the solution: law enforcement, regulatory, commercial, and public health entities must work together both within their borders and around the world.
One vital part play in this coalition process prevention of illicit manufacture and trafficking of synthetic drugs, detecting emerging drug threats and use patterns, promoting public health interventions and services to prevent and reduce drug use, overdose, and other health related problems

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It leads to unsafe life. Drug addiction not only breaks the family harmony but also puts high economic burden on the society. The economic impact due to Drug abuse is immeasurable. The use, production and marketing of drugs, emergence of a class of drug consumers is a huge challenge for mankind. It ultimately leads to unemployment, weak human resources, weak brain power, unhealthy society and increasing crime at large. The socioeconomic impact is associated with the expenditure incurred. We need to design a policy to prevent drug abuse. We must develop a prevention strategy and we need to educate the youth and protect the human resources. The impact is felt in various domains of life such as: family, industries, workplace and economy of the country. According to UNDCP report, the economic effects of drug abuse can be measured in two forms, i.e. cost of government drug enforcement polices and the lost human productivity such as lost wages and decreased production that results from illness and premature deaths related to drug abuse. There are many hidden costs relating to disturbance in social life, wastage of young energy and increased crimes. In simple terms socio-economic impact of drug abuse means undesirable or negative changes in the social fabric due to drug abuse; it also includes negative economic impact on individual, society and Government. It has many aspects. Use of drug by common people leads to many social consequences such as – Instability in family relationship, Domestic Violence, Crime prone life, Reduction of sense of belongingness to the family and the society. There is also lack of social harmony and happiness within the family. On the other hand, family plays an important role in the life of an individual. Family members have a strong bond with each other, they support each other, face crisis together and affect the behavior and attitude of each other. Once any member becomes a drug addict the entire family is negatively affected. The family can play a major role in preventing drug addiction within the family. Further even if unfortunately a member becomes a drug addict, deaddiction is impossible without the support of the family. Doctors alone cannot cure a drug addict without the support of the family. Use of drugs by any family member particularly the parents and the elders negatively affect the young ones. Weak family link also reduces its influence for preventing drug abuse. It has been found that use of drugs by elders leads to use by youngsters. Use of drugs by a family member creates a vicious circle of drug users and its leads to a drug prone society. Family is the basic unit of the society. The harmony of the family depends on the family members. When one member of family becomes drug abuser then he disturbs the entire family harmony. Every family member suffers due to a single drug abuser. It affects the life style, behavior, personality formation of the children and also financial condition of the family. The money spent on drugs can be put to better use. Amongst the poor the spending on drugs deprives others from food. The nation also pay heavy price in terms of workforce and from economic point of view relating to absenteeism, lack of performance and accidents at work place are the common problems created by the drug abusers. The drug abusers show criminal attitude in family. It ultimately breaks down the family bondage. Parents of young drug abuser suffer a lot. Parents cannot face the child who is taking drugs and behaves abnormally. When the younger ones observe the elders using drugs, they wrongly assume that drug abuse is an accepted behavior. The family members ultimately accept this with anger, fear, shame and embarrassment. Drug abuser in family generally shows socially unacceptable behaviors, violence, aggression, irresponsibility and selfishness. Many addicts also indulge in gambling. Drug addicts in the family affect children negatively. They create fear amongst children. When the Kumar
International Police OrganizationSerbiaIn Serbia there is a very little information about synthetic drugs. Users, especially young people often think that a pill is safe, that cocaine is always pure and only with natural content . We need support for stong campaign against synthetic drugswww.iposrbija.rsIlija
INTERPOL CENTER UNCanadawww.un-ipc.comwww.un-ipc.comVALERII
Journey ngoMaldivesI strongly recommend governments to address the synthetic drug threat through a balanced approach consisting of supply, demand and harm reduction. International pressure could be important to move countries that have remained stagnant in addressing national drug challenges, leaving the challenge to escalate. Additionally countries such as the Maldives were resources are scarce need international support that could empower us to mitigate the devastating effects of synthetic drugs. We need research to understand the shift form depressants to stimulant use among our drug users, to better be able to formulate targeted interventions.Ali
MainlineNetherlandsFor any initiative to be successful, the people concerned should not only be engaged or consulted, but should have a position of influence in the design of the initiative, as well as in it's management, implementation and monitoring.

Background information: (old, but not outdated).
MENANPUDPakistanTo effectively address the synthetic drug threat, the Global Coalition should focus on comprehensive strategies that encompass both supply and demand reduction measures. This includes:

Enhanced international cooperation: Strengthening collaboration among countries to share intelligence, resources, and best practices in combating synthetic drug trafficking networks.
Targeted law enforcement efforts: Prioritizing investigations and interdictions to disrupt the production, distribution, and sale of synthetic drugs, particularly through coordinated operations targeting key trafficking routes and organizations.
Capacity building: Supporting capacity-building initiatives in countries affected by synthetic drug trafficking to improve their ability to detect, investigate, and prosecute synthetic drug-related crimes.
Public health approach: Implementing evidence-based prevention, treatment, and harm reduction programs to reduce demand for synthetic drugs and mitigate their impact on individuals, families, and communities.
Research and innovation: Investing in research and innovation to better understand emerging synthetic drug trends, develop new detection methods, and identify effective interventions to address the evolving nature of the synthetic drug threat.
Multilateral partnerships: Engaging with international organizations, such as the United Nations Office on Drugs and Crime (UNODC) and the World Health Organization (WHO), as well as regional and non-governmental organizations, to leverage their expertise and resources in addressing the synthetic drug challenge on a global scale.
By adopting a multifaceted approach that combines law enforcement, public health, research, and international cooperation, the Global Coalition can work towards reducing the production, trafficking, and consumption of synthetic drugs and protecting public health and safety worldwide.

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NANSANA DIVISION COALITION AGAINST DRUGSUgandaUnveiling the Harmful Surge of New, Inexpensive Alcoholic Beverages and Their Impact on Youth Mortality in Nansana Division as an emerging threat.

Background Information:
The Nansana Division Coalition Against Drugs, a community-based organization, initiated a research project to investigate the alarming rise of inexpensive alcoholic beverages in the local market and their potential contribution to the untimely deaths of young individuals. This study aimed to shed light on the prevalence and impact of these newly emerging brands on the community's youth.
Organization of the fight Against Narcotics, Prohibited Drinks, Smoking and Alcoholism (OLCOS)BurundiMy contribution is based on the criminal justice system, including alternatives to incarceration as well as synthetic drug trafficking. It is expected that all Governments around the world will put in place effective laws and strategies to combat drug trafficking by mobilizing their police and legal institutions

Background information:
The information I want to share with others is how drug trafficking and its consumption have become a serious threat to developing countries as well as developing countries.
REAJUDMozambiqueWe intend to learn more about synthetic drug addiction treatment.
Harm Reduction or drug verification programs do not yet address synthetic drugs, although they exist and are gaining an ever-growing market.
Rotary Action Group for Addiction PreventionBelgiumPrevention: Project Youth Prevention Influencers (YPI) in line with UNODC Youth Initiative, RAG AP is developing a training for trainers to train candidate YPI, selected by Rotary clubs in cooperation with local NGO's. After their training YPI's are encouraged and supported to develop their own prevention actions in their own youth environment also supported by ongoing evaluation by an academic institute to enable permanent adaptation of their actions. A pilot is running in Belgium, dissemination in EU will follow end of 2024 and International in 2025 throughout the international network of Rotary clubs and districts.www.rag-ap.orgJohan